Royal Air Force Typhoon FGR4s have joined forces with French warplanes in a combined operation against an subterranean weapons facility in Syrian territory used by the IS group, as stated by the UK's MoD.
The site, located using intelligence, was thought to be containing munitions and bombs, the statement said, and was positioned in mountainous terrain just to the north of Palmyra in Syria's central region.
"The RAF jets employed laser-guided Paveway IV weapons to hit a number of approach shafts providing entry to the facility... preliminary assessments indicate the target was engaged successfully," the ministry announced.
There was no indication of any civilian casualties in the strike late on Saturday and every plane involved returned to base without incident, the MoD added.
The Typhoon fighters were supported by a Voyager tanker plane.
The Islamic State group - referred to as the so-called Islamic State - established militant control over large swathes of Syria and Iraq until 2019.
"This action demonstrates British leadership, and resolve to operate in unison with allied nations, to eradicate any re-emergence of Daesh and their violent and radical beliefs in the area," Britain's Defence Chief John Healey stated.
RAF aircraft have conducted surveillance missions over Syria to "prevent any attempted resurgence" of the group subsequent to its routing at the Baghuz confrontation in the year 2019, the ministry said.
"I want to thank all the members of our armed forces involved in this strike for their skill and their courage," he added. "They were among thousands of British troops on duty over the festive period. This action, to remove militants who endanger our security, shows how our armed forces are prepared to act, continuously, protecting the UK at home and influential overseas."
Last December, the American forces carried out what it termed a "major assault" targeting Daesh sites in the country, following an assault resulted in the deaths of two American soldiers and a civilian interpreter in Palmyra.
The United Nations estimates IS still boasts roughly 5-7 thousand fighters in Syria and Iraq.
